New ‘super antibody’ discovery that fights Covid variants, making current vaccines obsolete

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The finding is an opportunity for the creation of new vaccines

A group of researchers from Cancer Fred Hutchinson in Seattle, United States, discovered a super antibody capable of fighting variants of the SARS-CoV-2 virus.

This discovery is encouraging for the scientific community as it could help develop new vaccines and treatments for variants of the new coronavirus.

To arrive at this result, the article This ‘super antibody’ for Covid fights off multiple coronaviruses, published in the journal Nature, indicates the analysis of 12 antibodies isolated from people who had recovered from Covid-19 and compiled a list of thousands of mutations of the variants, both of the new coronavirus and of other similar viruses.

The study shows that the antibodies adhere to a fragment of viral protein that binds to receptors on human cells, termed the “receptor-binding domain,” and how the mutations affect the ability of the 12 antibodies to adhere to the domain.

In this way, the discovery of the S2H97 antibody, called Pansabecovirus, was possible, which can prevent a range of variants of SARS-CoV-2 and other viruses from spreading between cells.

Closer examination of the molecular structure of S2H97 revealed that it targets a previously invisible and well-hidden region in the binding domain, a section that is revealed only when the domain appears to bind to a cell’s receptor, thus, Given the great protection it offers, it could be used for the creation of new more effective vaccines.

Mexico Daily Post